Astana 0-2 Kairat Almaty
Atlético Madrid 1-1 Villarreal
Slovácko 0-3 Slavia Praha
Maccabi Tel-Aviv 5-2 Hapoel Akko

Group B

Skënderbeu 2-0 Luftëtari
Young Boys 5-1 Sion
Borac Čačak 1-2 Partizan
Karpaty Lviv 1-1 Dynamo Kyiv

Group C

Hoffenheim 1-3 Mönchengladbach
Başakşehir 2-1 Akhisar Belediyespor
Braga 1-0 Chaves
Ludogorets 2-0 Levski Sofia

Group D

Dinamo Zagreb 3-1 Rijeka
AC Milan 0-2 Juventus
Linz 2-2 Austria Wien
Panionios 0-1 AEK Athens

Group E

Udinese 2-1 Atalanta
Lyon 2-0 Metz
Leicester City 2-0 Everton
Apollon Limassol 4-2 Doxa

Group F

Sheriff 1-1 Sfintul Gheorghe Suruceni
Bohemians 1905 1-1 Zlín
Zenit 0-3 Lokomotiv Moskwa
Horsens 1-1 København

Group G

Karviná 1-3 Viktoria Plzeň
Lugano 1-0 Luzurn
Clubul Sportiv U Craiova 2-5 FCSB
Ashdod 1-3 Hapoel Beer-Sheva

Group H

Bayer Leverkusen 2-1 Köln
Arsenal 2-1 Swansea City
BATE 1-1 Naftan
Zemun 0-1 Crvena zvezda

Group I

Salzburg 2-0 Altach
Konyaspor 1-0 Osmanlıspor
LOSC Lille 0-1 Marseille
Aves 1-3 Vitória SC

Group J

Östersund 4-1 Elfsborg
Hertha Berlin 2-1 Hamburg
Athletic Club 0-2 Barcelona
Zorya 2-2 Oleksandria

Group K

Paris Saint-Germain 3-0 Nice
Zulte Waregem 2-1 Mechelen
Vitesse 2-4 PSV Eindhoven
Benevento 1-5 Lazio

Group L

Getafe 2-1 Real Sociedad
Sileks 0-0 Vardar
Zenit 0-3 Lokomotiv Moskva
Rosenborg 0-0 Stabæk